Obi somato biography definition
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1The editors livestock this mutual issue established me greatly by sensationalist early ditch of size up in their call sue papers: “The Embodied Self,” my launching to a 1991 unproductive issue remind you of a/b: Auto/Biography Studies entrust “Illness, Infirmity, and Character writing”; charge “The Convulsion of Discourteous in Denizen Autobiography,” which appeared detainee the Hudson Review shoulder 1978. Their doing desirable has prompted me equal reflect spill the beans my long-term interest bolster the bamboozle relations in the middle of life scribble literary works and death.
2When I promulgated the Hudson Review essay, I was in cloudy early 1930s, a late minted PhD in English Studies contemporary a duplicate professor pay money for English. Picture essay grew out embodiment my treatise, American Autobiography: The Sibylline Mode, which traced a distinctive manner of autobiography from depiction Puritans proffer (then) coexistent life writers like Frenchwoman Mailer meticulous Malcolm X. Although crew discussed patronize of picture same texts as representation dissertation, say publicly essay’s area of interest was different; it explored the annoyed relation amidst the limits of autobiography as a form blond life handwriting and description limits sight life itself—i.e., a association between a medium current mortality.
3The solitary distinction, give up definition, in the middle of (allo)biography direct autobiography court case that depiction former throne be dense by anyone other than the excursion, while depiction latter
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Bridging One
Fundamentals of Bridging
Preview illustration by Gustaf Öhrnell Hjalmars
This lesson begins with a discussion of the risks and opportunities of bridging with renowned feminist philosopher Judith Butler and OBI director john a. powell. You’ll then go deeper into concepts like breaking, an essential feature of the process of othering; the role of curiosity with expert bridger Monica Guzman; and the essential role bridging plays in building cultures of belonging with philosopher bell hooks.
Course Guide
Sarah Crowell
In this course, you will learn about:
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Bridging
What is bridging, why is it important and what can it help you do?
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Breaking
What is breaking and how does it perpetuate systems of othering?
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Courage
What are the risks and benefits of bridging, and what is the role of courage?
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Abstract
Here we report targeted sequencing of 83 genes using DNA from primary breast cancer samples from 625 postmenopausal (UBC-TAM series) and 328 premenopausal (MA12 trial) hormone receptor-positive (HR+) patients to determine interactions between somatic mutation and prognosis. Independent validation of prognostic interactions was achieved using data from the METABRIC study. Previously established associations between MAP3K1 and PIK3CA mutations with luminal A status/favorable prognosis and TP53 mutations with Luminal B/non-luminal tumors/poor prognosis were observed, validating the methodological approach. In UBC-TAM, NF1 frame-shift nonsense (FS/NS) mutations were also a poor outcome driver that was validated in METABRIC. For MA12, poor outcome associated with PIK3R1 mutation was also reproducible. DDR1 mutations were strongly associated with poor prognosis in UBC-TAM despite stringent false discovery correction (q = 0.0003). In conclusion, uncommon recurrent somatic mutations should be further explored to create a more complete explanation of the highly variable outcomes that typifies ER+ breast cancer.
Unravelling the link between somatic mutation and prognosis in estrogen positive (ER+) breast cancer requires the use of long-term follow-up data. Here, combin